XL1017 Acute Lymphoblastic Leukemia PDX Model

Model Information:

N/A

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Summary:

CategoryParameterModel Detail (XL1017)
IdentityModel IDXL1017
Cancer TypeAcute Lymphoblastic Leukemia (ALL)
Model TypePDX (Patient-Derived Xenograft)
Clinical BackgroundPatient Age9
Patient GenderMale
EthnicityCaucasian
DiagnosisB-cell Acute Lymphoblastic Leukemia
StageNewly Diagnosed
Sample SiteBone Marrow
Genomics & BiomarkersPrimary DriverZNF384-Rearranged (EP300-ZNF384)
CytogeneticsN/A
WES (Whole Exome)N/A
RNA-SeqN/A
CNV ProfileN/A
Mutational LoadN/A
CharacterizationSurface MarkersCD19+, CD10+/-, CD34+, CD13+, CD33+
Host StrainNSG
Inoculation RouteIV
Growth KineticN/A
PharmacologySoC ResponseN/A
Immune ProfilingN/A
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Growth Characteristics:

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