XL1014 Acute Lymphoblastic Leukemia PDX Model

Model Information:

N/A

Category	Parameter	Model Detail (XL1014)
Identity	Model ID	XL1014
	Cancer Type	Acute Lymphoblastic Leukemia (ALL)
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	19
	Patient Gender	Male
	Ethnicity	Hispanic
	Diagnosis	B-cell Acute Lymphoblastic Leukemia
	Stage	Relapsed
	Sample Site	Bone Marrow
Genomics & Biomarkers	Primary Driver	JAK2 R683G Mutation
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	CD19+, CD10+, CD34+, CRLF2+
	Host Strain	NSG
	Inoculation Route	IV
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A