Model Information:
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Request a Custom Quote for XB6003 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB6003) |
| Identity | Model ID | XB6003 |
| Cancer Type | Breast Cancer | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 62 |
| Patient Gender | Female | |
| Ethnicity | N/A | |
| Diagnosis | Invasive Ductal Carcinoma (IDC) | |
| Subtype / Receptor Status | ER(+), PR(+), HER2(-) | |
| Stage | Stage IIA (pT2 N0 M0) | |
| Sample Site | Primary Breast Tumor | |
| Genomics & Biomarkers | Primary Driver | PIK3CA Mutation / MAP3K1 Mutation |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | ER+, PR+, GATA3+, E-cadherin+, Ki-67 (Low-to-Moderate, ~15-20%) |
| Host Strain | NSG (Requires 17β-estradiol supplementation) | |
| Inoculation Route | Orthotopic (Mammary Fat Pad) | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
