Model Information:

Pleomorphic xanthoastrocytoma of the frontotemporal region, WHO grade II.

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Summary:

Category	Parameter	Model Detail (XB5010)
Identity	Model ID	XB5010
	Cancer Type	Brain Cancer
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	26
	Patient Gender	Female
	Ethnicity	N/A
	Diagnosis	Pleomorphic Xanthoastrocytoma (PXA)
	Stage	WHO Grade 2 (Grade II)
	Sample Site	Frontotemporal Brain Mass
Genomics & Biomarkers	Primary Driver	BRAF V600E Mutation / CDKN2A/B Deletion
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	GFAP+, S100+, CD34 (Focal), Reticulin meshwork (Positive), Ki-67 (Low-to-Moderate)
	Host Strain	NSG (NOD scid gamma)
	Inoculation Route	Orthotopic / Subcutaneous
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A

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Growth Characteristics:

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