Model Information:

n/a

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Summary:

Category	Parameter	Model Detail (XB5004)
Identity	Model ID	XB5004
	Cancer Type	Brain Cancer
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	14
	Patient Gender	Male
	Ethnicity	N/A
	Diagnosis	Medulloblastoma (SHH Subgroup)
	Stage	WHO Grade 4
	Sample Site	Cerebellum / Posterior Fossa
Genomics & Biomarkers	Primary Driver	PTCH1 / SMO Mutation
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	Synaptophysin+, NeuN+, GAB1+, Ki-67 (High)
	Host Strain	NSG (NOD scid gamma)
	Inoculation Route	Orthotopic (Cerebellar) / Subcutaneous
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A

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Growth Characteristics:

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