XB4009 Bladder Cancer PDX Model

Model Information:

Transitional cell carcinoma of the bladder; poorly differentiated tumor involving most of the sampled tissue with malignant cells present in cytologic preparations.

Request a Custom Quote for XB4009 Xenograft Model

Summary:

CategoryParameterModel Detail (XB4009)
IdentityModel IDXB4009
Cancer TypeBladder Cancer
Model TypePDX (Patient-Derived Xenograft)
Clinical BackgroundPatient Age77
Patient GenderMale
EthnicityN/A
DiagnosisPoorly Differentiated Transitional Cell Carcinoma
StageHigh-grade / Advanced
Sample SiteBladder Tissue (Cytology positive)
Genomics & BiomarkersPrimary DriverTP53 / MDM2 Amplification
CytogeneticsN/A
WES (Whole Exome)N/A
RNA-SeqN/A
CNV ProfileN/A
Mutational LoadN/A
CharacterizationSurface MarkersGATA3 (Variable), CK7+, Ki-67 (High)
Host StrainNSG (NOD scid gamma)
Inoculation RouteSubcutaneous
Growth KineticN/A
PharmacologySoC ResponseN/A
Immune ProfilingN/A
Request a Custom Quote for XB4009 Xenograft Model

Growth Characteristics:

Request a Custom Quote for XB4009 Xenograft Model