Model Information:
Infiltrative low-grade urothelial carcinoma of the bladder with metastatic involvement of a single regional lymph node.
Request a Custom Quote for XB4005 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB4005) |
| Identity | Model ID | XB4005 |
| Cancer Type | Bladder Cancer | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 65 |
| Patient Gender | Female | |
| Ethnicity | N/A | |
| Diagnosis | Low-grade Infiltrative Urothelial Carcinoma | |
| Stage | pT2 N1 (Lymph Node Involvement) | |
| Sample Site | Regional Lymph Node | |
| Genomics & Biomarkers | Primary Driver | FGFR3 Mutation |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | GATA3+, CK7+, CK20 (Low), Ki-67 (Moderate) |
| Host Strain | NSG (NOD scid gamma) | |
| Inoculation Route | Subcutaneous | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
