Model Information:
Spindle cell tumor of the bladder with features consistent with leiomyosarcoma; tumor arranged in fascicles with elevated mitotic activity and invasion through the bladder wall.
Request a Custom Quote for XB4003 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB4003) |
| Identity | Model ID | XB4003 |
| Cancer Type | Bladder Cancer (Sarcomatoid) | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 62 |
| Patient Gender | Male | |
| Ethnicity | N/A | |
| Diagnosis | Leiomyosarcoma of the Bladder | |
| Stage | High-grade (Muscle-invasive) | |
| Sample Site | Bladder Wall | |
| Genomics & Biomarkers | Primary Driver | TP53 / RB1 Loss |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | SMA+, Desmin+, Vimentin+, Ki-67 (High) |
| Host Strain | NSG (NOD scid gamma) | |
| Inoculation Route | Subcutaneous | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
