Model Information:

Anaplastic meningeoma, WHO grade III, arising from meningeal tissue with invasion into brain parenchyma and mixed epithelial and fibrous features.

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Summary:

Category	Parameter	Model Detail (XB5008)
Identity	Model ID	XB5008
	Cancer Type	Brain Cancer
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	66
	Patient Gender	Female
	Ethnicity	N/A
	Diagnosis	Anaplastic Meningioma (Mixed Epithelial/Fibrous)
	Stage	WHO Grade 3 (Grade III with Parenchymal Invasion)
	Sample Site	Meningeal Mass / Invaded Brain Tissue
Genomics & Biomarkers	Primary Driver	NF2 Loss / BAP1 Mutation / CDKN2A/B Deletion
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	EMA+, Vimentin+, E-cadherin (Focal), Ki-67 (High, >20%)
	Host Strain	NSG (NOD scid gamma)
	Inoculation Route	Orthotopic / Subcutaneous
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A

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Growth Characteristics:

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