Model Information:

Anaplastic oligodendroglioma, WHO grade III, with positive glial markers and a moderate proliferative index on immunohistochemistry.

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Summary:

Category	Parameter	Model Detail (XB5007)
Identity	Model ID	XB5007
	Cancer Type	Brain Cancer
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	51
	Patient Gender	Male
	Ethnicity	N/A
	Diagnosis	Anaplastic Oligodendroglioma
	Stage	WHO Grade 3 (Grade III)
	Sample Site	Brain (Frontal/Temporal Lobe)
Genomics & Biomarkers	Primary Driver	IDH1 Mutation & 1p/19q Co-deletion / TERT Promoter
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	Olig2+, IDH1-R132H+, ATRX (Retained), Ki-67 (Moderate, ~15-20%)
	Host Strain	NSG (NOD scid gamma)
	Inoculation Route	Orthotopic / Subcutaneous
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A

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Growth Characteristics:

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