Model Information:
Pleomorphic glioblastoma of the frontal lobe with marked nuclear atypia, microvascular proliferation, hemorrhage, and palisading necrosis, consistent with WHO grade IV.
Request a Custom Quote for XB5005 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB5005) |
| Identity | Model ID | XB5005 |
| Cancer Type | Brain Cancer | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 58 |
| Patient Gender | Male | |
| Ethnicity | N/A | |
| Diagnosis | Pleomorphic Glioblastoma (Frontal Lobe) | |
| Stage | WHO Grade 4 (Grade IV) | |
| Sample Site | Frontal Lobe (Resected Mass) | |
| Genomics & Biomarkers | Primary Driver | TP53 / PTEN / EGFR Amplification |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | GFAP+, Nestin+, Olig2+, IDH1 (Wildtype) |
| Host Strain | NSG (NOD scid gamma) | |
| Inoculation Route | Orthotopic / Subcutaneous | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
