Model Information:
Meningioma with diffuse tumor involvement in examined sections and malignant cells detectable in cytologic preparations.
Request a Custom Quote for XB5003 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB5003) |
| Identity | Model ID | XB5003 |
| Cancer Type | Brain Cancer | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 63 |
| Patient Gender | Female | |
| Ethnicity | N/A | |
| Diagnosis | Meningioma (Diffuse Involvement) | |
| Stage | Grade II / III (High-Grade Features) | |
| Sample Site | Brain (Meninges / Cytologic Material) | |
| Genomics & Biomarkers | Primary Driver | NF2 Loss / TRAF7 Mutation |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | EMA+, Vimentin+, Ki-67 (Elevated) |
| Host Strain | NSG (NOD scid gamma) | |
| Inoculation Route | Subcutaneous / Orthotopic | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
