Model Information:

Infiltrating urothelial carcinoma of the bladder with extension through the bladder wall.

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Summary:

Category	Parameter	Model Detail (XB4008)
Identity	Model ID	XB4008
	Cancer Type	Bladder Cancer
	Model Type	PDX (Patient-Derived Xenograft)
Clinical Background	Patient Age	70
	Patient Gender	Female
	Ethnicity	N/A
	Diagnosis	Infiltrating Urothelial Carcinoma
	Stage	pT3b (Extension through bladder wall into perivesical fat)
	Sample Site	Bladder (Cystectomy)
Genomics & Biomarkers	Primary Driver	TP53 / ERBB2 (HER2)
	Cytogenetics	N/A
	WES (Whole Exome)	N/A
	RNA-Seq	N/A
	CNV Profile	N/A
	Mutational Load	N/A
Characterization	Surface Markers	GATA3+, CK7+, HER2+, p63+
	Host Strain	NSG (NOD scid gamma)
	Inoculation Route	Subcutaneous
	Growth Kinetic	N/A
Pharmacology	SoC Response	N/A
	Immune Profiling	N/A

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Growth Characteristics:

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