XB4001 Bladder Cancer PDX Model

Model Information:

Poorly to moderately differentiated squamous cell carcinoma.

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Summary:

CategoryParameterModel Detail (XB4001)
IdentityModel IDXB4001
Cancer TypeBladder Cancer
Model TypePDX (Patient-Derived Xenograft)
Clinical BackgroundPatient Age68
Patient GenderMale
EthnicityN/A
DiagnosisSquamous Cell Carcinoma of the Bladder
StageMuscle-Invasive (T2)
Sample SiteBladder (Transurethral Resection)
Genomics & BiomarkersPrimary DriverTP53 / PIK3CA
CytogeneticsN/A
WES (Whole Exome)N/A
RNA-SeqN/A
CNV ProfileN/A
Mutational LoadN/A
CharacterizationSurface MarkersCK5/6+, p63+, GATA3-
Host StrainNSG (NOD scid gamma)
Inoculation RouteSubcutaneous
Growth KineticN/A
PharmacologySoC ResponseN/A
Immune ProfilingN/A
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Growth Characteristics:

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