XA3001 Adrenal Gland Cancer PDX Model

Model Information:

High‑grade carcinoma originating in the adrenal region with local extension into adjacent soft tissue; immunohistochemistry supportive of neuroendocrine differentiation.

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Summary:

CategoryParameterModel Detail (XA3001)
IdentityModel IDXA3001
Cancer TypeAdrenal Gland Cancer
Model TypePDX (Patient-Derived Xenograft)
Clinical BackgroundPatient Age54
Patient GenderMale
EthnicityN/A
DiagnosisHigh-grade Adrenal Carcinoma (Neuroendocrine differentiation)
StageLocally Advanced (Soft Tissue Extension)
Sample SiteAdrenal Mass
Genomics & BiomarkersPrimary DriverNeuroendocrine Markers (Chromogranin A/Synaptophysin+)
CytogeneticsN/A
WES (Whole Exome)N/A
RNA-SeqN/A
CNV ProfileN/A
Mutational LoadN/A
CharacterizationSurface MarkersNCAM+, SF-1+, Ki-67 (High)
Host StrainNSG (NOD scid gamma)
Inoculation RouteSubcutaneous
Growth KineticN/A
PharmacologySoC ResponseN/A
Immune ProfilingN/A
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Growth Characteristics:

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