Model Information:
Infiltrative urothelial carcinoma with squamous and adenoid differentiation, extending to the adventitia and forming discrete tumor nodules.
Request a Custom Quote for XB4004 Xenograft ModelSummary:
| Category | Parameter | Model Detail (XB4004) |
| Identity | Model ID | XB4004 |
| Cancer Type | Bladder Cancer | |
| Model Type | PDX (Patient-Derived Xenograft) | |
| Clinical Background | Patient Age | 72 |
| Patient Gender | Male | |
| Ethnicity | N/A | |
| Diagnosis | Infiltrative Urothelial Carcinoma (Mixed Differentiation) | |
| Stage | pT3b (Extension to Adventitia) | |
| Sample Site | Bladder (Cystectomy) | |
| Genomics & Biomarkers | Primary Driver | FGFR3 / PIK3CA |
| Cytogenetics | N/A | |
| WES (Whole Exome) | N/A | |
| RNA-Seq | N/A | |
| CNV Profile | N/A | |
| Mutational Load | N/A | |
| Characterization | Surface Markers | GATA3+, CK7+, CK20+, p63+ |
| Host Strain | NSG (NOD scid gamma) | |
| Inoculation Route | Subcutaneous | |
| Growth Kinetic | N/A | |
| Pharmacology | SoC Response | N/A |
| Immune Profiling | N/A |
Growth Characteristics:
